DDT Dehydrochlorinase
نویسندگان
چکیده
منابع مشابه
DDT dehydrochlorinase. II. Substrate and cofactor specificity.
In Paper I (1) of this series methods of purification and measurement of DDT dehydrochlorinase’ were described. Those physical and chemical properties that could be determined with the small amounts of purified enzyme available were presented. It was shown that proton liberation from the tertiary carbon atom of DDT (C-2) was not stimulated at alkaline pH although the enzyme possesses considerab...
متن کاملDDT dehydrochlorinase. I. Isolation, chemical properties, and spectrophotometric assay.
The dehydrochlorination of 1 , 1 , I-trichloro-2,2-bis(p-chlorophenyl)ethane to its nontoxic, ethylenic analogue, DDE,* by extracts of DDT-resistant houseflies (1Musca domestica) was first demonstrated by Sternburg et al. (I). It was shown that this system was GSH-dependent and that no DDT dehydrochlorinase could be detected in DDT-susceptible flies by the means then available. The titer of DDT...
متن کاملNovel LinA type 3 δ-hexachlorocyclohexane dehydrochlorinase.
LinA is the first enzyme of the microbial degradation pathway of a chlorinated insecticide, hexachlorocyclohexane (HCH), and mediates the dehydrochlorination of α-, γ-, and δ-HCH. Its two variants, LinA type 1 and LinA type 2, which differ at 10 out of 156 amino acid residues, have been described. Their activities for the metabolism of different HCH isomers differ considerably but overall are h...
متن کاملSusceptibility of Aedes albopictus from China to insecticides, and mechanism of DDT resistance.
Aedes albopictus collected from urban districts of China (12 strains) has developed high levels of DDT resistance, while 2 strains collected from rural areas remain susceptible. The mechanism of DDT resistance was due to intensified activity of DDT-dehydrochlorinase, but the penetration of DDT into the mosquito body is also different. This may possibly have had some influence on the resistance ...
متن کاملDDT Paradox
Hwang B-F, Lee YL, Jaakkola JJ. 2011. Air pollution and stillbirth: a population-based case–control study in Taiwan. Environ Health Perspect 119:1345–1349; http://dx.doi. org/10.1289/ehp.1003056 [Online 29 March 2011]. Strand L, Barnett A, Tong S. 2011. Methodological challenges when estimating the effects of season and seasonal exposures on birth outcomes. BMC Medical Research Methodology 11 (...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1959
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)69877-1